• Timeline
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    Menstrual Cycle: Introduction

    The average length of the menstrual cycle is 28 days. More

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    Menstrual Cycle: Days 1-5

    Day 1 of menstruation is the first day of your cycle. More

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    Menstrual Cycle: Days 1-13

    Days 1-13 of your menstrual cycle are the "follicular phase" More

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    Menstrual Cycle: Days 10-18

    Days 10-18 of your menstrual cycle are considered the "ovulatory phase". More

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    Menstrual Cycle: Days 15-28

    Days 15-28 of your menstrual cycle are considered the "luteal phase". More

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    IUI: Introduction

    With intrauterine insemination (IUI), a doctor uses a soft catheter to place sperm directly into the uterus. More

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    IUI: Day 1

    Fertility drug injections begin at the start of the your menstrual cycle. More

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    IUI: Day 2

    Follicles begin to respond to the fertility drugs and grow. More

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    IUI: Day 3

    Daily fertility drug injections cause your follicles to continue to grow. More

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    IUI: Day 4

    Your follicles continue to grow. More

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    IUI: Day 5

    As the follicles respond to the fertility drugs, your doctor will monitor your progress with vaginal ultrasound. More

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    IUI: Day 6

    Your body is producing more estrogen and your uterine lining begins to thicken. More

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    IUI: Day 7

    Fertility drug injections continued and you are monitored for ovulation. More

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    IUI: Day 8

    Daily fertility drug injections continue and follicles continue to grow. More

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    IUI: Day 9

    Your follicles are still developing and you continue fertility drug injections. More

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    IUI: Day 10

    You discontinue using injectable fertility drugs. More

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    IUI: Day 11

    The hCG trigger shot is injected to help follicles mature and release the eggs. More

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    IUI: Day 12

    Your follicles and eggs are almost mature. More

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    IUI: Day 13

    Ovulation occurs. More

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    IUI: Day 14

    Sperm is washed and you are inseminated when you are ovulating. More

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    IUI: Day 15

    The embryo, now in the fallopian tube, will continue to divide. More

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    IUI: Day 16

    The embryo continues to grow. More

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    IUI: Day 17

    The embryo travels from the fallopian tube to the uterus. More

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    IUI: Day 18

    Hormone levels continue to increase. More

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    IUI: Day 19

    The uterine lining is now 8-12 mm thick. More

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    IUI: Day 20

    Your embryo is working to ultimately attach to the lining of your uterus. More

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    IUI: Day 21

    Your embryo will attach to your uterine lining. More

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    IUI: Day 22

    The embryo is starting to implant. More

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    IUI: Day 23

    The embryo continues to implant. More

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    IUI: Day 25

    Your body begins to produce hCG and progesterone production continues. More

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    IUI: Day 26

    The embryo continues to grow, and progesterone support continues. More

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    IUI: Day 27

    The embryo continues to grow. More

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    IUI: Day 28

    A blood pregnancy test will determine if you are pregnant. More

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    IVF: Introduction

    More

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    IVF: Day 1

    On Day 1 of your IVF cycle, you'll begin fertility drug injections. More

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    IVF: Day 2

    On Day 2 of your IVF cycle, you'll continue fertility drug injections. More

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    IVF: Day 3

    Your follicles continue to grow as they respond to the fertility drug injections. More

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    IVF: Day 4

    Your follicles continue to grow as you continue daily fertility drug injections. More

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    IVF: Day 5

    As you continue to use fertility drugs you will be monitored by your fertility doctor. More

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    IVF: Day 6

    The lining of your uterus is beginning to thicken as you continue fertility drug injections. More

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    IVF: Day 7

    Daily fertility drug injections continue, and your fertility doctor may start monitoring hormone levels. More

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    IVF: Day 8

    You'll continue fertility drug injections and follicles will continue to grow. More

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    IVF: Day 9

    You'll continue fertility drug injections and follicles will continue to grow. More

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    IVF: Day 10

    You'll stop using fertility drugs at this point in your IVF cycle. More

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    IVF: Day 11

    Once your body has responded to the fertility drugs, you'll receive an hCG injection (trigger shot) and egg retrieval will be scheduled. More

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    IVF: Day 12

    Your eggs are almost mature, and are ready for egg retrieval. More

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    IVF: Day 13

    At this stage of the IVF cycle, your eggs are retrieved and fertilized. More

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    IVF: Day 14

    Your eggs are fertilizing in the lab. More

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    IVF: Day 15

    Embryos will continue to develop, and if PGD has been scheduled the procedure will take place. More

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    IVF: Day 16

    Usually on Day 16 of your IVF cycle your embryo transfer will take place. More

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    IVF: Day 17

    The embryo is in your uterus, and cells continue to divide and increase. More

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    IVF: Day 18

    The embryo continues to grow and hormone levels increase. More

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    IVF: Day 19

    The lining of your uterus is now 8-12 mm thick. More

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    IVF: Day 20

    Your embryo is working to attach to the lining of your uterus. More

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    IVF: Day 21

    The embryo attaches to the uterine lining. More

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    IVF: Day 22

    The embryo begins to implant in the uterine lining. More

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    IVF: Day 23

    The embryo continues implanting in the uterine lining. More

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    IVF: Day 24

    More

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    IVF: Day 25

    Your embryo continues to grow and progesterone continues to be produced. More

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    IVF: Day 26

    Your implanted embryo continues to grow. More

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    IVF: Day 27

    The implanted embryo continues cell division. More

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    IVF Cycle: Day 28

    It's time to take a blood pregnancy test. More

Frustrated with Your Diagnosis of Unexplained Infertility?

Frustrated with Your Diagnosis of Unexplained Infertility?

Infertility is defined as the inability to get pregnant after one year of unprotected intercourse if you are a female under the age of 35, or six months if you are 35 or older. Women who get pregnant but who have repeated miscarriages are also considered infertile.

Unexplained infertility means that medical tests cannot find any cause for infertility. In some cases, all the tests come back normal even though the couple is unable to conceive. In other cases, the tests may uncover minor abnormalities, but they are not severe enough to result in infertility.

It can be frustrating not to know exactly what is causing the problem. If you have unexplained infertility you are not alone: unexplained infertility affects about 1 in 5 couples.

What Causes It?

Diagnosed infertility in women may be caused by a number of factors. For example, it might be that the egg is not released at the best time for fertilization or that fertilization does not happen at all. Blocked fallopian tubes, uterine fibroids, or uterine problems may also be the cause.

Men can also have fertility problems which result in the couple being unable to conceive. Infertility in men is often due to few or no sperm cells being produced. In some cases, the sperm might be misshapen or they might die before they can reach and fertilize the egg.

A woman is more likely to be diagnosed with unexplained infertility if she is 38 or older. As women get older, the quantity and quality of their eggs diminishes. Most women over 40 have a hard time conceiving, and women over age 44 are rarely fertile even if they ovulate regularly every month. Since there is no test to check for egg quality or quantity, older women with fertility problems are often diagnosed as having unexplained fertility.

Women with mild endometriosis may also have fertility problems. Since it is not proven that mild endometriosis causes infertility, some researchers consider those women as having unexplained infertility.

Is There Any Chance of Conceiving?

The length of time you have been infertile is an important factor in whether you will conceive. Couples who have been infertile for 5 years have less than a 10 percent chance of being able to conceive on their own. Some couples with unexplained infertility have success getting pregnant using intrauterine insemination (IUI) or ovulation induction with fertility drugs. If you do not get pregnant within 3 to 6 treatment cycles, you may want to try in vitro fertilization (IVF) which uses an egg fertilized by sperm outside the womb to achieve pregnancy.

Learn more about unexplained infertility:
Unexplained Infertility: Diagnosis & Treatment

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