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How Fertility Drugs Help You Ovulate

The goal of fertility drugs is to help eggs mature for ovulation or egg retrieval. With intrauterine insemination (IUI), your fertility doctor may instruct you to use fertility drugs to produce a greater number of follicles for ovulation. Here is what you need to know about how fertility drugs help you ovulate:

Clomid or Serophene. Clomid or Serophene are first line fertility drugs that help a woman ovulate. Fertility patients are instructed to take the drug orally for five days, usually between cycle day three and cycle day nine. Clomid and Serophene work by blocking the estrogen receptors in a woman’s brain. Follicle stimulating hormone (FSH) production increases, as does Leutinizing Hormone (LH). Once follicles grow and eggs mature, your body prepares for ovulation.

Gonadotropins. Injectable fertility drugs like Repronex, Menopur, Follistim, Bravelle, and Gonal-F contain FSH and may also contain LH, both of which stimulate the ovaries to produce follicles. Gonadotropins are typically administered beginning on day three of your cycle, and may continue for up to 14 days. Once follicles near maturity, your fertility doctor will instruct you to take a human choronic gonadotropin (hCG) injection.

Human Chorionic Gonadotropin (hCG). This hormone helps with the final maturation of eggs and gives a push toward ovulation. Ovulation usually takes place approximately 24-36 hours after the hCG trigger shot.

Leading up to ovulation, your fertility doctor may also instruct you to use to use an Ovulation Prediction Kit (OPK). This test is designed to test for LH surge which signals ovulation is near. You will then be instructed to report to your fertility clinic for the IUI procedure.

If you are having trouble trying to conceive, a fertility doctor can evaluate your hormone levels and let you know if fertility drugs with IUI is the right protocol for you. Contact our Patient Care Advocates at 1-855-955-BABY (2229) or by filling out the Contact Fertility Doctors Near Me form.

Watch as Dr. Eric Flisser of RMA New York answers: "How Do I Know if I am Ovulating?":


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