• Timeline
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    Menstrual Cycle: Introduction

    The average length of the menstrual cycle is 28 days. More

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    Menstrual Cycle: Days 1-5

    Day 1 of menstruation is the first day of your cycle. More

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    Menstrual Cycle: Days 1-13

    Days 1-13 of your menstrual cycle are the "follicular phase" More

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    Menstrual Cycle: Days 10-18

    Days 10-18 of your menstrual cycle are considered the "ovulatory phase". More

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    Menstrual Cycle: Days 15-28

    Days 15-28 of your menstrual cycle are considered the "luteal phase". More

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    IUI: Introduction

    With intrauterine insemination (IUI), a doctor uses a soft catheter to place sperm directly into the uterus. More

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    IUI: Day 1

    Fertility drug injections begin at the start of the your menstrual cycle. More

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    IUI: Day 2

    Follicles begin to respond to the fertility drugs and grow. More

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    IUI: Day 3

    Daily fertility drug injections cause your follicles to continue to grow. More

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    IUI: Day 4

    Your follicles continue to grow. More

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    IUI: Day 5

    As the follicles respond to the fertility drugs, your doctor will monitor your progress with vaginal ultrasound. More

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    IUI: Day 6

    Your body is producing more estrogen and your uterine lining begins to thicken. More

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    IUI: Day 7

    Fertility drug injections continued and you are monitored for ovulation. More

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    IUI: Day 8

    Daily fertility drug injections continue and follicles continue to grow. More

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    IUI: Day 9

    Your follicles are still developing and you continue fertility drug injections. More

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    IUI: Day 10

    You discontinue using injectable fertility drugs. More

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    IUI: Day 11

    The hCG trigger shot is injected to help follicles mature and release the eggs. More

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    IUI: Day 12

    Your follicles and eggs are almost mature. More

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    IUI: Day 13

    Ovulation occurs. More

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    IUI: Day 14

    Sperm is washed and you are inseminated when you are ovulating. More

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    IUI: Day 15

    The embryo, now in the fallopian tube, will continue to divide. More

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    IUI: Day 16

    The embryo continues to grow. More

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    IUI: Day 17

    The embryo travels from the fallopian tube to the uterus. More

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    IUI: Day 18

    Hormone levels continue to increase. More

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    IUI: Day 19

    The uterine lining is now 8-12 mm thick. More

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    IUI: Day 20

    Your embryo is working to ultimately attach to the lining of your uterus. More

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    IUI: Day 21

    Your embryo will attach to your uterine lining. More

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    IUI: Day 22

    The embryo is starting to implant. More

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    IUI: Day 23

    The embryo continues to implant. More

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    IUI: Day 25

    Your body begins to produce hCG and progesterone production continues. More

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    IUI: Day 26

    The embryo continues to grow, and progesterone support continues. More

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    IUI: Day 27

    The embryo continues to grow. More

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    IUI: Day 28

    A blood pregnancy test will determine if you are pregnant. More

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    IVF: Introduction

    More

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    IVF: Day 1

    On Day 1 of your IVF cycle, you'll begin fertility drug injections. More

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    IVF: Day 2

    On Day 2 of your IVF cycle, you'll continue fertility drug injections. More

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    IVF: Day 3

    Your follicles continue to grow as they respond to the fertility drug injections. More

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    IVF: Day 4

    Your follicles continue to grow as you continue daily fertility drug injections. More

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    IVF: Day 5

    As you continue to use fertility drugs you will be monitored by your fertility doctor. More

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    IVF: Day 6

    The lining of your uterus is beginning to thicken as you continue fertility drug injections. More

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    IVF: Day 7

    Daily fertility drug injections continue, and your fertility doctor may start monitoring hormone levels. More

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    IVF: Day 8

    You'll continue fertility drug injections and follicles will continue to grow. More

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    IVF: Day 9

    You'll continue fertility drug injections and follicles will continue to grow. More

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    IVF: Day 10

    You'll stop using fertility drugs at this point in your IVF cycle. More

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    IVF: Day 11

    Once your body has responded to the fertility drugs, you'll receive an hCG injection (trigger shot) and egg retrieval will be scheduled. More

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    IVF: Day 12

    Your eggs are almost mature, and are ready for egg retrieval. More

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    IVF: Day 13

    At this stage of the IVF cycle, your eggs are retrieved and fertilized. More

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    IVF: Day 14

    Your eggs are fertilizing in the lab. More

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    IVF: Day 15

    Embryos will continue to develop, and if PGD has been scheduled the procedure will take place. More

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    IVF: Day 16

    Usually on Day 16 of your IVF cycle your embryo transfer will take place. More

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    IVF: Day 17

    The embryo is in your uterus, and cells continue to divide and increase. More

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    IVF: Day 18

    The embryo continues to grow and hormone levels increase. More

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    IVF: Day 19

    The lining of your uterus is now 8-12 mm thick. More

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    IVF: Day 20

    Your embryo is working to attach to the lining of your uterus. More

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    IVF: Day 21

    The embryo attaches to the uterine lining. More

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    IVF: Day 22

    The embryo begins to implant in the uterine lining. More

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    IVF: Day 23

    The embryo continues implanting in the uterine lining. More

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    IVF: Day 24

    More

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    IVF: Day 25

    Your embryo continues to grow and progesterone continues to be produced. More

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    IVF: Day 26

    Your implanted embryo continues to grow. More

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    IVF: Day 27

    The implanted embryo continues cell division. More

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    IVF Cycle: Day 28

    It's time to take a blood pregnancy test. More

Negative Pregnancy Test: You've Missed a Period But Your Test is Negative

Negative Pregnancy Test: You've Missed a Period But Your Test is Negative

It can be very frustrating for a woman to experience a late period and a negative pregnancy test. Whether or not you are trying to conceive, these conflicting results can lead to a great deal of stress, worry and confusion. You want answers quickly: Am I pregnant? If so, why am I getting a negative pregnancy test result? If not, then where is my period?

There are a several possible explanations for the mixed results. In many cases there may be explanations other than pregnancy for why your period is late. There are also possible situations where a missed period is indeed caused by a pregnancy, but you nevertheless receive a negative pregnancy test result.

If you’ve missed a period and are experiencing some early pregnancy symptoms, but your home pregnancy test is negative, you could experiencing a "false negative” pregnancy test. Here are some reasons why:

Miscalculating your period. The average menstrual cycle is 28 days. So, if you are fortunate enough to have a regular 28-day cycle, you would count 28 days from the start of your last menstrual cycle to determine when your next period is due. However, many women do not have a 28-day cycle and even if you do, this does not account for variations in ovulation dates and more importantly the date of implantation. Taking a pregnancy test at the wrong time will yield a negative result.

Home pregnancy test with a low sensitivity. A home pregnancy test will only detect pregnancy when the level of “pregnancy hormone” Human Chorionic Gonadotropin (hCG) reaches a certain threshold, and it simply may not be sensitive enough to produce a positive result. Try again with a more sensitive brand. Shop for pregnancy tests here.

Directions weren’t followed properly. Another reason for a “false negative” result is that directions weren’t followed carefully enough to ensure the accuracy of the test. There is a possibility that while using a home pregnancy test strip you either did not dip it well or did not hold it well in your urine stream. This error in technique may give false negative results. It is also essential that you read the test results in the stipulated reaction time. Do not discard a kit until the completed reaction time has elapsed (typically between 5 and 10 minutes). On the other hand, if you let the test sit for too long, the test is invalid.

Early Detection Attempt. Another reason for a false negative pregnancy test could be that you took the test too early. Pregnancy tests vary in how soon they can detect hCG in your urine. It is possible that although an egg may be fertilized, your body has not started secreting enough hCG to register on a test. Your body needs time for the hormone to rise to a high enough level to be detected. Most brands instruct you to wait until the first day of your missed period to conduct the test.

Poor Urine Sample. In some cases, a woman may drink a great deal of fluids before collecting a urine sample, thereby diluting the amount of hCG present in the urine. This could cause a negative result. Avoid drinking a lot of fluids before testing. Also, it’s usually best to use a first morning urine sample. If your schedule prevents this, try to hold your urine for several hours before collecting a sample.

hCG Develops at Different Rates Among Women. Some women can easily discover if they are pregnant well before their missed period, while others may need to wait a bit longer. The amount of hCG in your urine rises each day following the implantation of the fertilized egg in the womb. These rates can vary, and thus produce different results. In addition, in some cases, hCG antibodies in the test will not "bind" as well with the particular hCG hormone composition of a pregnant woman. This can result in receiving a slightly delayed positive result. While this is quite unusual, it may explain many of the complaints about even the most expensive and sensitive test brands causing delayed positives after a missed period.

Problem With the Pregnancy/Ectopic Pregnancy. In rare cases, low or falling hCG levels may indicate a problem or an ectopic pregnancy. If you have missed your period and are experiencing pregnancy symptoms, contact your doctor to take a blood hCG test to determine the cause of the missed period, or an unexplained negative test result.

There may be reasons for having a missed or very late period that have nothing to do with being pregnant. Here are some explanations:

Irregular Cycles. For some women, being late now and then is part of their "normal" pattern. Other factors that can influence a missed period are increased stress, anxiety, or sleeplessness. Long periods of stress or anxiety can affect the balance of reproductive hormones and delay ovulation or the onset of menstruation. Other causes for irregularity are travel and jet-lag, excessive exercise and being overweight or underweight. Of course, if you are on birth control, or have recently discontinued birth control, you may experience missed periods as well. If you have any questions about your medications, talk to your prescribing doctor.

Peri-menopause. Premature menopause can be a cause of a missed period. Only a doctor can accurately diagnose this, although you can test for early menopause at home with an FSH test. Levels indicating high FSH on day three of your cycle may indicate that your body is working overtime to stimulate follicular development. FSH tests may suggest a low ovarian reserve (peri-menopause) requiring a follow up test with your physician.

If you have received a negative test result a day or two after your period is due, it may be caused by one of the explanations above. Retest again in a week, and if you still haven’t gotten your period and your pregnancy test is still negative, consult your doctor. If you receive a negative pregnancy result after fertility treatments, talk to your RE about why the procedure may have failed and what steps to take next.

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