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Sherman J Silber M.D.
Sherman J. Silber, M.D., is a fertility doctor at The Infertility Center of Saint Louis, a Saint Louis, MO, fertility clinic. The Infertility Center of Saint Louis serves infertility patients from St. Louis and across the United States.
A renowned pioneer in microsurgery and infertility, Dr. Silber is considered one of the world’s leading authorities on in vitro fertilization (IVF), sperm retrieval, ICSI, vasectomy reversal, tubal ligation reversal, egg and embryo freezing, ovary transplantation, and the reproductive biological clock.
Dr. Sherman Silber treats St. Louis infertility patients and infertility patients from every state in the United States, as well as infertility patients from Europe, Asia, South America, the Middle East and Africa.
Considered one of the world’s leading authorities on in vitro fertilization (IVF), sperm retrieval, ICSI, vasectomy reversal, tubal ligation reversal, egg and embryo freezing, ovary transplantation, and the reproductive biological clock, Dr. Sherman Silber uses the following fertility treatments at his Saint Louis, MO, fertility clinic, including:
Dr.Sherman Silber is a renowned pioneer in microsurgery and infertility. Dr. Silber and his Saint Louis fertility clinic specialize in treating very difficult cases of infertility, e.g. where there has been previous failure to fertilize, failure to achieve pregnancy in previous efforts, or failed attempts at vasectomy reversal, etc. Dr. Silber is also happy to treat simpler infertility cases if so requested.
Dr. Silber and his Saint Louis fertility clinic treat the many causes of infertility, including:
Dr. Sherman Silber has been on the forefront of the new advances in the field of infertility. In the 1970s, he performed the world’s first microsurgical vasectomy reversal, as well as the first testicle transplant. More recently, Dr.Silber performed the world’s first ovary transplant. Additionally, he was the first to develop the TESE and MESA techniques for retrieving testicular and epididymal sperm for men with azoospermia.
Dr. Sherman Silber’s contributions to the field of infertility research have been numerous and varied. Dr. Silber headed the clinical MIT team that first mapped and sequenced the Y chromosome in infertile men and discovered the now famous DAZ gene for male fertility. Dr.Silber's research includes the study of reproduction and fertility in zoo animals and endangered species. Most recently, Dr Sherman Silber has perfected the preservation of fertility for cancer patients with ovarian freezing and transplantation, and thereby figured out how to extend the reproductive biological clock of women. Dr.Silber also helped pioneer minimal ovarian stimulation to reduce IVF costs.
As reported by Infertility Center of St. Louis, St. Luke's Hospital in St. Louis, Missouri to the CDC in 2010, the fertility clinic performed 45 donor egg cycles in that year; 18 cycles used fresh donor eggs and 27 cycles used frozen donor eggs.
| Clinic Name | City | Fresh Donor Eggs | Fresh Live Births | Frozen Donor Eggs | Frozen Live Births |
| Infertility Center of St. Louis, St. Luke's Hospital | ST. LOUIS | 18 | 6 / 18 | 27 | 37 |
According to the most recent report published by the CDC, Infertility Center of St. Louis, St. Luke's Hospital in St. Louis, Missouri performed 137 IVF cycles in 2010. The number of IVF cycles and babies born, broken down by patients' age is as follows:
| Clinic Name | City | Number of Cycles by Age | Live Birth Rate By Age (%) | ||||||||
| <35 | 35-37 | 38-40 | 41-42 | 43-44 | <35 | 35-37 | 38-40 | 41-42 | 43-44 | ||
| Infertility Center of St. Louis, St. Luke's Hospital | ST. LOUIS | 79 | 32 | 16 | 6 | 4 | 44.3 | 31.3 | 7 / 16 | 1 / 6 | 0 / 4 |
Since infertility treatment is expensive, Dr. Sherman J. Silber and his Saint Louis fertility clinic try to soften its impact by achieving the highest possible pregnancy rates, thus reducing the number of treatment attempts and the overall expense.
Dr. Silber and the Infertility Center of Saint Louis do not charge extra for unnecessary testing or ineffective preliminary treatment approaches. Dr. Silber only recommends what he feels is necessary to help you achieve a pregnancy as soon as possible.
Dr. Silber and his Saint Louis fertility clinic have no hidden extra charges added on, which might result in much higher costs at some fertility clinics. For example, there is no additional charge for office visits, semen analysis and/or sperm freezing, embryo freezing, assisted hatching, blastocyst culture, or ICSI, which is always performed in every case to give you the greatest chance for pregnancy. Also, Dr. Silber does not order an expensive list of purely remunerative tests with procedures that just delay the most cost-effective treatment.
Couples often ask if there is a discount for subsequent in vitro fertilization (IVF) cycles if they don't get pregnant with the first IVF cycle. With Dr. Silber's vitrification technique for embryo freezing, the pregnancy rate for subsequent frozen embryo transfers is just as high as for fresh IVF, but the cost is only one quarter the cost of a regular IVF cycle. Furthermore, Dr. Silber and his Saint Louis fertility clinic's "mini-IVF" technology dramatically reduces your cost as well.
Sherman J. Silber, M.D., earned his medical degree at University of Michigan and completed post-graduate training at Stanford University and again at the University of Michigan.
Dr. Sherman Silber is a member of American Association of Bioanalysts, American Society for Reproductive Medicine , the American Urological Association, Australian Fertility Society, European Society for Human Reproduction and Embrylogy, an honorary member of the Korean Urological Association, Pacific Coast Fertility Society, Preimplantation Genetic Diagnosis International Society, and Royal Society of Medicine, England.


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