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Multiple Egg Donation Does Not Impair Fertility

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October 20, 2013

Egg donation does not impair a womans’ future fertility according to researchers at Weill Cornell Medical College in New York City. This is exciting news for women who may have been previously concerned that donation of their eggs would hamper their own fertility later in life. A study of all egg donor charts over an 8 year period identified women who had completed five or more egg donation cycles, including the donors’ Anti-Mullerian Hormone (AMH) levels, amount of hormonal medication given, length of time the donor was stimulated, and the number of eggs retrieved.

It was found that the average age at first donation was 26.4 and, at fifth cycle 28.7. During all of the donors’ cycles, similarities were noted in the average days of stimulation, and the number of eggs retrieved. The average number of days stimulated ranged from 9.4 to 10 and an average number of eggs retrieved ranged from 20.9-23.8. Gonadotropins, the class of medication used for stimulation, were slightly lower in the first cycle, but the total amount used over all cycles was comparable.

"This retrospective study is reassuring in that egg donors who undergo up to 6 cycles do not have evidence of depleting their ovarian reserve, which bodes well for their future fertility" notes ASRM President Linda Giudice, MD, PhD. "It also underscores the importance of careful monitoring of egg donors prior to starting medication in order to minimize the risk of ovarian hyperstimulation syndrome."


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