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Natural Cycle IVF for Low Sperm Count and Irregular Menstrual Cycles

a blog by Dr. Andrea Reh, Dominion Fertility, July 22, 2014

Dr. Reh here to share a success story of a lovely couple known to me since last year. W.S. is a 33-year-old woman with infertility for over two years. W.S. had irregular menstrual cycles, which had initially been the target of treatment from her OBGYN prior to our meeting. However, as with all couples, we encouraged them to have a comprehensive evaluation upfront to evaluate for all possible causes of infertility.

Her husband’s semen analysis showed a very low sperm count, making it highly unlikely that they would conceive without IVF (in vitro fertilization) with ICSI (intracytoplasmic sperm injection). The husband was thoroughly evaluated by a urologist and we discussed all of our options. Even though W.S. had slightly irregular menstrual cycles, we decided together to give Natural cycle IVF a try, acknowledging that it would require more than the average amount of “monitoring” to get the timing just right.

On their first cycle of Natural cycle IVF, we transferred a nice 8-cell embryo on day 3, but without pregnancy. As with all couples, we met after their failed cycle, discussed options and attempted to troubleshoot about how we could improve. On their second cycle, the egg did not fertilize after ICSI, but just to be certain we gave it an extra day in culture. A testament to the unpredictability of biology, the egg did fertilize late that day and developed nicely into a morula for transfer.

We are proud to report that W.S. conceived and is moving along nicely in her second trimester after this successful Natural Cycle IVF. Congratulations and best wishes!


Comments (2)

I have PCOS and have been pretty regular 31-34 days on Metformin, could I do NCIVF?

Hi Neeta,

You should consult with the doctor to determine if you are a candidate for Natural Cycle IVF. Send me an email and I will gladly set you up for a consultation with one of the doctors at Dominion Fertility.


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