Taxonomy term

A sperm DNA fragmentation assessment can help determine appropriate fertility treatment in infertile men with normal semen parameters who have a failed IUI cycle. A recent study by Weill Cornell Medical College analyzed the efficiency of different fertility treatment methods by comparing pregnancy rates between normal and abnormal sperm DNA fragmentation cohorts in relation to IUI, IVF and IVF with ICSI. The researchers determined, “For men with compromised sperm DNA fragmentation in their ejaculate, ICSI confirms to be the best insemination method with ejaculated sperm. For men who have compromised sperm nuclear DNA that failed ICSI, a testicular sampling yielded superior clinical outcome.”

The implantation rate of slower developing blastocysts (day 5 embryos) is a result of asynchrony of the embryo and the endometrium, not the quality of the embryo, according to data presented by Reproductive Medicine Associates of NY (RMA of NY). However, the implantation rate is improved if the slower developing embryos are frozen, then thawed and transferred to a well-prepared, controlled uterine environment.

A recent study compared the efficacy of two types of preimplantation genetic screening (PGS) used with IVF and single embryo transfer: next generation sequencing (NGS), and array Comparative Genomic Hybridization (aCGH). The researchers determined that clinical and ongoing pregnancy rates are comparable.

PGD and Frozen Embryo Transfers yield higher pregnancy rates than fresh embryos! What is FET? What is PGD? “The problems with IVF are pretty well known: pregnancy rates are not as good as they should be".