As specialists in reproductive endocrinology, we are often asked what steps a couple can take to best prepare them to conceive and carry a pregnancy to term. While taking these steps certainly does not guarantee conception or that a pregnancy can be carried full term, they will increase the chances of conception and a healthy pregnancy.
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From the Blog of Fertility Doctor Allen Morgan
Dr. Allen Morgan is board certified in reproductive endocrinology, an Assistant Clinical Professor at the University of Medicine and Dentistry of New Jersey (UMDNJ), and a member of The Society for Advanced Laparoscopic Surgery and the American Society for Reproductive Medicine (ASRM). His embryology laboratory has consistently been certified by the College of American Pathology (CAP), FDA, and the Society of Assisted Reproductive Technologies (SART) since 1996.
In PCOS, the follicle never reaches a size big enough to ovulate so the ovary doesn’t produce progesterone and the uterus has no signal to tell it whether to bleed or not, causing infrequent menstruation. Eventually the lining may grow so thick, waiting for the progesterone, that it becomes unstable and sloughs off in an erratic way causing unpredictable bleeding every day or quite heavy bleeding. If progesterone is absent for many months, the lining sometimes gets so thick from the “unopposed” estrogen that the cells can become abnormal, precancerous or even cancerous. Since the follicles never rupture, month after month they fill up in the ovary and create a line of small cysts right near the surface of the ovary, giving the classic “polycystic” appearance. The term “polycystic” means “many cysts” of the ovary, but these are not so much cysts as they are immature, un-ruptured follicles. They are not harmful or cancerous cysts.