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Ovarian Androgen Production in Postmenopausal Women

Wednesday, August 1, 2007

Several studies previously reported that the postmeno-pausal ovary produces androgens. However, these findings have re-cently been questioned in a group of women with adrenal insufficiency. We sought to use contemporary assay methodologies to investigate whether the postmenopausal ovary is hormonally active and contributes to the circulating pool of androgens.

Conclusions: The postmenopausal ovary is hormonally active, contributing significantly to the circulating pool of T. Furthermore, this contribution appears to persist in women as long as 10 yr beyond the menopause.

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