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When undergoing a fertility work-up, a woman will typically have a blood test to measure AMH — antimullerian hormone — levels. This test is helpful in assessing ovarian reserve and whether a woman has premature ovarian aging or premature ovarian failure.
AMH is a substance produced by the granulosa cells in the ovarian follicles. As a woman ages, the number of ovarian follicles decreases, which decreases the blood AMH levels. Women with polycystic ovarian syndrome (PCOs), a condition in which there are many small ovarian follicles, tend to have high AMH levels. Women with few remaining follicles, such as women who are close to menopause, have low AMH levels.
Research has shown that women with higher concentrations of AMH have a better response to ovarian stimulation and tend to produce more retrievable eggs for IVF (in vitro fertilization) than women with low or undetectable AMH.
AMH is but one test to assess your ovarian reserve. Others include tests for follicle stimulating hormone (FSH), estradiol levels, the clomiphene citrate challenge test (CCCT), and an ultrasound examination of the antral follicles. Talk to your fertility doctor about each test and how it can give you more information about your potential for a successful IVF.