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Secondary Infertility: Causes, Diagnosis, and Treatment

Although you may have conceived your first child without any trouble, it is still possible to experience secondary infertility.

“Secondary infertility refers to couples who have had a successful pregnancy in the past, but then experience difficulty with conceiving. Part of this may be explained by age, especially if their last pregnancy was achieved in their late thirties or early forties,” says Dr. Matthew Lederman of RMA New York. Secondary infertility may make it difficult for a couple to conceive on their own and could require fertility treatments ranging from ovulation induction drugs to in vitro fertilization (IVF).

Some of the most common causes of secondary infertility include:

  • Age related decline in ovarian reserve.
  • Increased risk of miscarriage due to age.
  • Continuing issues similar to primary infertility such as ovulation disorders, tubal infertility, male factor infertility, or endometriosis.

A diagnosis of secondary infertility is reached after ovarian reserve testing (blood work and ultrasound), examination of the uterus and fallopian tubes, a semen analysis for the male partner have been completed.

To learn more about secondary infertility and how it is treated, check out Dr. Matthew Lederman’s blog on

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