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How Long Should I Be on Clomid?

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After you have had a basic fertility work-up that indicates you are not ovulating regularly or not ovulating at all, your fertility doctor may prescribe Clomid (clomiphene citrate). Clomid is most often used to stimulate ovulation in women who have infrequent or absent ovulation (anovulation).

What Is the Dosage for Clomid?

Clomid is an oral fertility drug that comes in 50 milligram (mg) tablets. The standard dosage is 50 mg a day for five consecutive days, usually starting on the second, third, fourth or fifth day after menstruation begins.

The fertility doctor will determine your response to Clomid and whether you are ovulating through a number of means which may include: your menstrual pattern, ovulation predictor kits, measurement of serum progesterone levels or the basal body temperature (BBT) chart. If ovulation does not occur at the 50 mg dosage, the fertility doctor will increase Clomid by 50 mg increments in each cycle until you ovulate.

It is important to note that even though dosages in excess of 100 mg are not approved by the Food and Drug Administration, your fertility doctor will determine the right dose for you.

How Long Should I Stay on Clomid?

Recommendations are that you stay on Clomid for a maximum of six months.

“Estrogen normally has a negative effect on the pituitary,” says David Kreiner, M.D., a New York fertility doctor with East Coast Fertility. “Clomid blocks estrogen and leads to pituitary FSH production and ovarian stimulation.” Clomid causes the pituitary gland to secrete more FSH, and the higher level of FSH spurs the development of ovarian follicles that contain eggs. If the treatment is successful, about a week after the last table of Clomid is taken, the pituitary gland releases a luteinizing hormone surge, which causes the egg to be released.

“Women who are likely to conceive with Clomid usually do so in the first three months of therapy,” Dr. Kreiner says, “with very few conceiving after six months.”

Because Clomid has an anti-estrogen effect, it can have an adverse effect on the cervical mucus and endometrial lining. “Clomid may thin out her cervical mucus, preventing the sperm’s entrance into her womb,” Dr. Kreiner says.

In addition, a study done many years ago indicated that women who used Clomid for more than 12 cycles developed an increased incidence of ovarian tumors. “It is therefore recommended by the American Society of Reproductive Medicine (ASRM), as well as the manufacturer of clomiphene that Clomid be used for no more than six months, after which it is recommended by both groups that patients proceed with treatment including gonadrotropins (injectable hormones containing FSH and LH) to stimulate the ovaries in combination with intrauterine insemination or in vitro fertilization,” Dr. Kreiner says.


Comments (44)

I had all blood work done and everything came back in normal range. Tubal re anastomoses getting done. I'm remarried 38yrs old my REI doctor recommend I take day 3 of cycle... My fear is twins since all test were normal... Any thoughts?

Hello, I have polycystic ovaries. I hardly get period. Doctor advised me to take clomid 100 mg and I got pregnant from the first time we tried. Second time this year when we want another baby doctor only gave me 50mg first and then 75mg. Still no luck of getting pregnant. And this is the fifth cycle. I am so disappointed.I am thinking to buy clomid privetly and try again and again. please advice

Hello Jannet. I have a question maybe you can give me some advice. I was diagnosed with PCOS last year and was taking metformin 2000mg a day. It made me sick and I had to take a lesser dosage. It didn't work out for me so, they had me take progesterone, I got my cycle with no problem but, it's a form of birth control and since I'm trying to get pregnant. My Dr. Recently prescribed me Clomid 5 50mg pills. My only dilemma is, I haven't had a period since the end of January of this year and none before that. How do I really know when to start taking the clomid for it to work?

Hi there,

If you're having concerns regarding any medication that you've been prescribed or what your doctor has recommended I highly recommend that you get second opinion from a Board Certified Reproductive Endocrinologist. That way you can get to the bottom of why you haven't gotten your period and when is the best time to start taking the clomid for it to work. If you need help finding a specialist in your area feel free to email me directly at


Hi Jannet,

I strongly advise against purchasing Clomid and using it without a doctor's supervision. You may need to ask your doctor for the 100mg dose and see how your ovaries respond via blood work and ultrasound.

Best of luck,

Pls my doc says i should take clomid, wen can i start, after this wen should i start d 2nd one, & wen pls can i meet my husband, secondly, hw can i get twins with clomid. Pls enlighted me bcos am worried. Thanks.

Hi there,

Please consult your doctor about the appropriate dosing of Clomid. There is no guarantee of having twins with Clomid. Twin pregnancies are very risky for the mother and babies.

Good luck!

Hi everyone I am and clomid 50mg and metformin I start my first dose on 10 of october I was diagnos with pcos how soon I can get pregnant can't wait

Crystal, if you are confused by what the doctor told you regarding your clomid prescription you need to reach out to you doctor to get clarification on his or her orders so that you can understand and have your questions answered. Jenna

i was put on clomid 100mg but im wondering do you take the pills just the first month or do you take them each time you get your cycle please help... :)

Ana, if you are confused by what the doctor told you regarding your clomid prescription you need to reach out to you doctor to get clarification on his or her orders so that you can understand and have your questions answered.

Hello, my doctor gave me th clomid pills nd she told me that I should drink th pills on th second day of my periods which I started my periods on th 1st of August nd i started drinking the pills on th second nd she told me that I should have sex on the 12 of august,which mu man didn't want to understand nd we had sex on th 7 of August. I want to know if it can affect me or both of us or we should just have sex on date that the doctor have given us?pls help

Edith, if you are confused by what the doctor told you regarding your clomid prescription you need to reach out to you doctor to get clarification on his or her orders so that you can understand and have your questions answered.

I have been prescribed Clomid (once in May) and was taken off due to my Prolactin levels being WAY to high, I have had several test done and my Pituitary and Thyroid are fine. I recently saw a new OBGYN and he prescribed me 6 months of Clomid. However he did not mention that I needed to come back to have labs done after taking the medication. Is it important to have labs done after taking Clomid? Also I have been given Metformin. Is that good for ovulation?

Am 24 years old nd am struggling to conceive I wonder what could be the problem please help me

Hello Edith, when you are under the age of 35 years old doctors recommend that you actively try to conceive for 12 months while tracking your ovulation. Have you been tracking your ovulation? Do you have a regular period that comes at the same time each month? You can buy ovulation prediction kits at your local drug store to determine when you are most likely to conceive. If you have an irregular period you need to consult with your Gynecologist. If you haven't consulted with your Gynecologist yet you should set up an appointment with him or her to discuss your concerns.

Hello Lilly, did your OB/Gyn prescribe you clomid? How old are you? Once you've been on clomid for 3 months with no success it should be reevaluated. If you are concerned and would like to consult with a fertility specialist I am more than happy to help you find one in your area. Feel free to email me directly at

Hi JD,

Some doctors will instruct their patients to take Clomid from days 3-7 of their cycle, 4-8 of their cycle, or even 2-6 of their cycle. You should consult your doctor if you have any questions.


hi im 21 and was diognosed last year. the dr started me on 50g and on day 12 i had a scan and no leading follicle. she wasnts me to start new treatment in 3 days, could the follicle i have measring 10mm grow een bigger?

Hello Clare

I am so sorry to hear that you've been struggling / having concerns. These questions are best answered by your doctor. If you need a second opinion or would like to consult with a fertility specialist please feel free to email me directly at

Best of luck,

I hv pcos my doc gv me clomid at 1st bt I did nt concive, he than gv me another drugs wic I dnt knw d name bt d drugs z very expensive, I concieved nd later mc it at 6wks, after d and c my doctor gv me same drugs, I concieved and later had blighted ovum. My question z shuld I continue taking d drugs?

Hi Judith,

I am so sorry to hear of your losses. You should consult your doctor about continuing this treatment plan or making some changes to help you conceive.


i had a check up with my ob last week , because were worried last year of nov.i had a d&c blighted ovum its been 7months and yet im still not pregnant i read some blogs of having a BO but after a month they become pregnant ..thats why we decided to go the my OB first procedure i need to have an ultrasound to check my ovaryand thanks god my ovary has no problem ..after that my OB told me about sex timing and if still does not work ,,she prescribed me clomid that i will take 5days just excited but still worried were crossing our fingers and seeking for gods help ..we wish that it will effect very very soon ..we really want to have a baby..after all im still coping to my last BO...Thanks im just sharing

Princessrai - I'm sorry to hear that you're struggling and still coping with your last BO. Best of luck I hope that the clomid works! If at any point you would like to consult with a fertility specialist to see what other options are available to you please don't hesitate to email me directly at Good luck!!

Hai, I m 34 years old n been married for 3 yrs. My periods have been very irregular since before marriage. It stopped completely 2 1/2 yrs back. I consulted a gynea many times. There was no improvement. Now I want to conceive. I was put on clomid for 3 months n no result. Doctors give me no exact reason for stopped menstrual. Can u plz put some light on it.

Hi, I'm 29 yrs old and have PCOS. My doctor gave me clomid but is clomid one time drug? Or do you have to take it again next month? Please help.

Hi there,

Before you start taking the Clomid, make sure your partner has a semen analysis done. You want to make sure there isn't male factor infertility because if there is, Clomid might not help you conceive. Then, you should consider seeing a Reproductive Endocrinologist who will monitor you via blood work and ultrasound to see how you are responding to the Clomid. I have PCOS too and I really didn't respond as well as I had hoped to the Clomid. There is no way to know for sure if you aren't testing your blood and follicle growth. Clomid should not be taken for more than 3 to 6 months.

Give us a call if you would like to see a fertility doctor in your area. 855-955-BABY (2229).


Hi everyone just wanted to see if anyone can relate to me...I'm 26 been TTC for nearly 3years with my partner of 10years...had loads of tests, bloods, scans and lap and dye. Confirmed I'm just not ovulating :-( I have always had regular cycles. So that confused me! Started clomid in march and still not got pregnant...any tips or information would be lovely! I also use the ovulation calculator for a better chance of conceiving...x

Pre-seed is a great over the counter lube. It helps with getting pregnate. Got mine at Walmart. Good luck everyone!!! This is such a hard process for us all.

i took clomid in march during my cycle and after which i had to stop it cos of some side effect......i started with 50mg question is should i increase my dosage every month for six month

hi...please help...i am dignoised with PCOD and i was on clomid cycle 50 mg for 5 days ,but did not fall pregnant..i had a good follicle, only one.i am doing it again this month ,but my dr has reduced my dose to 25..i am wondering why she did this...inspite of having one good follicle she is reducing my dose.and i am so stressed why i didnt fall pregnant with the first cycle of clomid ,,is this normal

Hi everyone, How can someone increase the cervical mucus if they are taking Clomid? Is there an over the counter medication or home remedy? Thank You!

The length of your cycle will help you determine when you ovulate. You'll want to track that to make sure you are having sex around ovulation. If you miss your period, you should take a pregnancy test. If you don't get pregnant, it would make sense for you to see a fertility doctor - a reproductive endocrinologist. Let me know if you'd like more information. Best, Claire.

hi everyone, I'm 26, I met my husband Ray a year ago we tried to have a baby but never got pregnant, so I ask my doc to put me on something to help me, so he started me on clomid 50mg I started my first cycle of clomid on feb.14, I took my last pill on the 20th I was wondering when I should tested I usually get my cycles about the 12-17 every month,i have been feeling sleepy a lot, and I have gain a lot of weight and I can't fit in my clothes anymore could I be pregnant, is it possible to be pregnant that fast, my husband is the only guy I ever been with so I don't know about testing and when to it's all new to me. please reply back with some answers.

I am 23yrs old, i was diagonised of PCO nd i jst finished the last tablet of my first cycle yesterday. i started with 100mg and Am battling with the side effects. I want to know if the dosage is much for a start or not? And also to know when to test for pregnancy. Can i get pregnant with this first cycle?

Many doctors try clomid for PCOS and the dosage can range from 25mg to 150mg. Some, but not all, patients do get pregnant on the first cycle - for others it's 2 or 3 cycles, and most doctors would agree that if you're not pregnant in 3 to 6 cycles you should look at other treatment. You can use an ovulation predictor kit to determine when you're ovulating. It will depend on the length of your menstrual cycle. All the best, Claire

Yes it is possible to get pregnant the first cycle.. I have PCOS and I got pregnant my first cycle a year ago unfortunately it ended in a miscarriage, but I know next time I need to take progesterone supplements because I have very low levels which can end the pregnancy.. My advice is to take a test in about 2 weeks if its negative take another one I took clomid in January 13' found out I was pregnant in March 13'.. I finished 6 cycles in a year and this month Im starting again.. Good luck and baby dust to you :)

I am 24 yrs old and I just started my first attempt with clomid, its been a week now since i took the last tablet. I just want to know if it is possible for me to get pregz with the first cycle?

It is possible, but it depends on your particular situation. Many women who get pregnant with Clomid do so within the first three months. Your doctor will monitor your response. Keep us posted. Best, Claire

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