A sperm DNA fragmentation assessment can help determine appropriate fertility treatment in infertile men with normal semen parameters who have a failed IUI cycle. A recent study by Weill Cornell Medical College analyzed the efficiency of different fertility treatment methods by comparing pregnancy rates between normal and abnormal sperm DNA fragmentation cohorts in relation to IUI, IVF and IVF with ICSI. The researchers determined, “For men with compromised sperm DNA fragmentation in their ejaculate, ICSI confirms to be the best insemination method with ejaculated sperm. For men who have compromised sperm nuclear DNA that failed ICSI, a testicular sampling yielded superior clinical outcome.”
Male factor infertility plays a role in about approximately half of all cases of infertility. To understand what might be causing a couple's infertility, the male partner should undergo a fertility work-up.
A blog by Neway Fertility, December 23, 2014
Infertility affects about 3 million men in the United States. Many of these men seek help from a fertility clinic, but the success of any in vitro fertilization, or IVF, procedure and successful delivery depends on a healthy sperm and egg; healthy DNA is especially important to a healthy sperm and baby. Researchers may now be closer to understanding how a special protein may control how DNA information is packaged inside sperm.
Male infertility is not often discussed, and can be a challenging emotional hurdle to a couple who is trying to start or add to their family. Male infertility is caused by numerous factors such as medical conditions, medications, lifestyle choices involving alcohol, drug use, smoking, and environment. All of these factors can lead to low sperm counts, poor motility, and below average morphology scores...