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Controversial 'Third Parent' Technique can Double Chances of IVF Success for Older Woman

by Fiona Macrae,  Daily Mail U.K.,  Nov 12, 2009
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Older women's chances of motherhood more than doubled by mixing their eggs with material from a younger woman, doctors believe.
They have used eggs donated by young women to repair age-related damage to eggs and want to use them in fertility clinics.

Doing this greatly boost the odds of pregnancy, as well as cutting the cost and heartache of repeated failed IVF treatments.
But critics point out that any babies born this way would effectively have two mothers - and say the technique defies nature.

Damage to eggs means that IVF success rate falls sharply with age.
Although many of the problems are caused by damage to the DNA in the nucleus, others are thought to have their roots in the cytoplasm, the jelly-like material that makes up the bulk of the egg.

To create an egg with a healthy cytoplasm, the Japanese researchers took the nucleus from an older woman's egg and swapped placed it in a younger woman's egg which had had its nucleus removed. Read more.


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