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First Woman Gives Birth Twice with Ovary Transplant

by Maria Cheng,  Washington Post,  Feb 24, 2010
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When Stinne Holm Bergholdt of Denmark was diagnosed with bone cancer at age 27, she was afraid she wouldn't be able to have children.

So she asked her doctors if they could remove an ovary before her treatment and transplant it back afterward to preserve her fertility.

More than six years later, Bergholdt and her husband now have two daughters, making her the first woman in the world to give birth twice after an ovary transplant.

Details of her case were being published online Thursday in the journal, Human Reproduction.

"It's hard to believe it's really true," said Bergholdt, of Odense, Denmark. "It's like a dream that I never would have thought possible a few years ago."

On the day before she started chemotherapy, doctors took 13 strips of ovarian tissue from Bergholdt's right ovary and froze them. After eight months of cancer treatment and another year of recovery, doctors reimplanted seven of the strips, or about 20 percent of an entire ovary.
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