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FDA Adds Fertility Risk Warning to Label for the Cancer Drug Avastin

Wall Street Journal,  Oct 5, 2011

The FDA has added a new warning about the risk of "ovarian failure" to the label for the cancer drug Avastin, and it recommended doctors tell women of child-bearing age before they start treatment about the possibility that Avastin can cause ovaries to stop releasing eggs regularly. Avastin is approved to treat certain types of lung, brain, kidney, colon and breast cancers. However, in the U.S., the company is fighting to keep the FDA from revoking the approval for breast cancer. The label update announced Tuesday is separate from that pending decision.

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